Pet Supplement Toxicity: Products That Can Harm Dogs and Cats
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The “Natural” Products That Can Still Cause Real Harm
A little discussed, but very real issue in natural animal care is supplement toxicity. Most supplements are safe when they are made well and used correctly, but there are a few common ones that can cause serious problems. I am talking vomiting, diarrhea, tremors, liver issues, and even seizures in the wrong situation.
This is why I keep coming back to one simple rule. More is not better. And “human safe” does not mean “pet safe.”
Dr. Jones’ Complete Canine Calming Chews

Pet Supplement Toxicity: What Many Pet Parents Miss
Most of us assume supplements are generally safe. That belief gets a lot of pets into trouble. The problem is not supplements in general. The problem is high dosing, sloppy formulas, and sharing human products with dogs and cats.
Much of the newer toxicity information has been highlighted by veterinary toxicologist Dr. Tina Schmidt, and it is worth paying attention to.
Calming Chews and the Tryptophan Problem

When a dog is anxious, many pet parents reach for calming chews. Some contain tryptophan, an amino acid that can convert to serotonin in the brain. In low doses it can help. In excessive amounts it can trigger vomiting, diarrhea, tremors, depression, wobbliness, and in severe cases serotonin syndrome.
This is most often seen with poorly formulated products that add far more than is needed. If a label looks vague, or the company hides behind “proprietary blends,” that is not what you want.
Joint Supplements That Go Too Far

Glucosamine is widely used and very safe at appropriate doses. Problems arise when products push extreme amounts, or add extra minerals like manganese at levels that can worsen stomach upset and has been linked to more serious complications. If a product brags that it has massive doses compared to everything else, that is a warning sign, not a benefit.
Grass Saver Chews Are Not Worth the Risk

Products designed to prevent yellow grass often contain methionine to acidify the urine. Too much methionine can cause tremors and seizures, with effects that can last up to forty eight hours. My advice is simple. Avoid them, and manage lawn staining another way.
Human Supplements That Can Seriously Harm Pets
Vitamin D is one of the biggest issues I see. People take it often. Dogs and cats on balanced diets already get vitamin D, and extra supplementation can cause toxicity. I have seen kidney failure in cats from excess vitamin D.

Iron is another concern. Iron deficiency is common in people, but it is uncommon in pets. Overdose can cause severe digestive upset, shock, liver failure, and worse. If iron support is truly needed, whole foods like red meat are far safer than pills.
Lesser Known Dangers Many Miss

5-HTP is a human sleep and calming supplement that boosts serotonin and can cause serious neurologic effects in pets. Alpha lipoic acid is especially dangerous for cats, who are far more sensitive than dogs and can develop dangerously low blood sugar, tremors, and seizures.
And always check anything chewable or flavored for xylitol. It is now showing up in supplements, and it can cause a rapid blood sugar crash, seizures, coma, and even death.
The Safe Takeaway
Supplements can help, but they must be chosen carefully. Read labels. Avoid mega dosing. Choose reputable brands that clearly list ingredients and doses. When possible, rely on whole foods for nutrition.
That is also why we re formulated our Dog Calming Chews to remove tryptophan and include the extensively studied casein hydrolysate, alpha casozepine, along with L theanine, chamomile flower, valerian root, magnesium glycinate, and melatonin. It is designed to promote relaxation without drowsiness, and it is backed by more than a decade of research.
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P.S. Avoid giving human supplements to your pets, especially vitamin D and iron. Be cautious with chewable flavored products because of xylitol. And avoid excess tryptophan in any calming chew. Stick with trusted, proven brands.










